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The cell bioreactor working principle is mainly based on providing the appropriate environment and nutrients, and promoting the growth and metabolic process of microorganisms by controlling the parameters of gas concentration, pH value, temperature and agitation in the tank, so as to produce the required products.
Total volume | 5L,10L,15L,20L,30L,50L,100L,200L,500L,1000L, 5KL, 50KL, 200KL etc. |
Working volume | 30%~70% |
Tank | Jacket tank, made by SS316 and SS304, tank design pressure 0.3Mpa, jacket design pressure 0.35Mpa, polishing 0.4-0.6um, ratio of diameter and height is 1:2.2-2.5 |
Stirring system | Mechanical drive on the top/bottom or Magnetic drive on the top, 3pcs height adjustable six-blade paddle Stir speed: 50~1000rpm/50-400rpm |
Sterilization | Sterilize in place(SIP), auto control by program |
Clean | Clean in place (CIP) by spray ball |
Gas control | Control by rotor meter, air flow 1 vvm |
Feeding | Automatically feeding by peristaltic pump |
Anti-foam control | Automatically add antifoam by peristaltic pump |
Temperature control | Auto-control, electric heating range: water source add 5ºC to 70ºC |
PH control | PH 2.00-12.00±0.1, auto-control adding acid/base by peristaltic pump, pH sensor from Hamilton/Mettler, Switzerland. |
Do control | 0-150±3% displaying precision 0.1%, DO sensor from Hamilton/Mettler, Switzerland. DO coupling with agitation, oxygen. |
Sampling | Sampling valve, can sterilization separately, manual |
Lid lift system | 30L-500L have lid lift system, 700-1000L have human hole. |
Pressure | Auto control, BD Germany pressure transmitter |
Exhaust | Have condenser before exhaust, control by diagram valve / Proportional control valve. |
Control parameters | 10 or 15 inch touch screen , Siemens PLC with control parameters (stirring, pH, DO, temperature, feeding, alarm, gas etc.), data analysis, data record, data output, language(RU/EN/CN) and other customized functions |